Based upon their previous knowledge about common evolution and structure of haemoglobin and myoglobin, partial pressure of gases, and main properties of chemical elements and solutions, students may focus key principles of biology and chemistry of blood gases oxygen (O2) and carbon dioxide (CO2), and the mechanism regulating pH and hydro-electrolytic equilibrium of blood. Key principles are the followings: 1) gas diffusion and exchange into alveoli and tissue, 2) chemical equilibrium carbonic acid - bicarbonate anion, 3) pH and buffer solutions, 4) physical and chemical properties of iron, 5) the regulation of blood pH: alkalosis and acidosis. Furthermore this project is aimed at promoting use by the young of both common material and informatics technologies (PC, Internet, digital cameras and videos) to create models, hypertext, videos and any other useful approach to deepen into knowledge of key concepts in biology and chemistry of blood gases.